Mosquito-borne flaviviruses

Mosquitoes transmit flaviviruses including Dengue, Zika, West Nile and Japanese encephalitis virus. We study how these viruses hijack cellular processes in their human and mosquito hosts

Systems flavivirology

We use proteomics, transcriptomics and epigenomics to identify cellular pathways hijacked by viruses

Cellular Engineering

Viruses hijack cellular pathways so they can replicate. We use synthetic biology to control these same cellular pathways for biotechnology and biomedical applications

We are part of the College of Engineering and the College of Biological Sciences. We are located in 247 Briggs Hall.

The Shah Lab opened in 2017.  Interested in applying? Check out our contact page for more information!

The Shah Lab uses viruses and engineering principles to perturb and control biological networks. We are interested in exploring two major questions:

  1. How do flaviviruses hijack host machinery to facilitate their own replication?
  2. Can we control these biological networks for biomedical and biotechnology applications?

We use complementary techniques of global proteomics, genetics, high-throughput sequencing, microscopy and synthetic biology to tackle these questions.

November 2018: Welcome to postdocs Rob Stott (@robertjaystott) and Efra Rivera-Serrano (@nakedcapsid), and rotation students Adam Fishburn and Osman Sharifi

October 2018: Big changes in the lab. Fancy new microscope and biosafety cabinet arrive.

September 2018: Welcome to rotation students Tyler Laird and Nick DeCuzzi!

July 2018: The Shah lab turns one! Happy Birthday!

June 2018: Priya Shah receives the Gardner Fellowship from the Center for Comparative Medicine to develop a zebrafish microcephaly model. Let’s get our toes wet!

June 2018: The Montpetit, Fraser and Shah labs receive a Keck Foundation Award to study flavivirus-host interactions!