Mosquito-borne flaviviruses

Mosquitoes transmit flaviviruses including Dengue, Zika, West Nile and Japanese encephalitis virus. We study how these viruses hijack cellular processes in their human and mosquito hosts

Animal Models of Disease

We use zebrafish to study how Zika virus disrupts brain development

Cellular Engineering

Viruses hijack cellular pathways so they can replicate. We use synthetic biology to control these same cellular pathways for biotechnology and biomedical applications

We are part of the College of Engineering and the College of Biological Sciences. We are located in 247 Briggs Hall.

The Shah Lab opened in 2017.  Interested in applying? Check out our contact page for more information!

The Shah Lab uses viruses and engineering principles to perturb and control biological networks. We are interested in exploring two major questions:

  1. How do flaviviruses hijack host machinery to facilitate their own replication and cause disease?
  2. Can we control these biological networks for biomedical and biotechnology applications?

We use complementary techniques of global proteomics, genetics, high-throughput sequencing, high-throughput animal models, microscopy and synthetic biology to tackle these questions.

April 2021: Congratulations to Marine, Matthew and Ariana on their recent NS5-PAF1C pre-print!

February 2021: Bon voyage to Dr. Marine Petit. Best wishes to your new scientific adventures with the Marie Curie Fellowship!

January 2021: Congratulations to Shiaki Minami on publishing the first research article for the Shah lab!

November 2020: Welcome to Dr. Oanh Pham, a new postdoctoral scholar. We are thrilled to have you join the team