Mosquito-borne flaviviruses

Mosquitoes transmit flaviviruses including Dengue, Zika, West Nile and Japanese encephalitis virus. We study how these viruses hijack cellular processes in their human and mosquito hosts

Animal Models of Disease

We use zebrafish to study how Zika virus disrupts brain development

Cellular Engineering

Viruses hijack cellular pathways so they can replicate. We use synthetic biology to control these same cellular pathways for biotechnology and biomedical applications

We are part of the College of Engineering and the College of Biological Sciences. We are located in 247 Briggs Hall.

The Shah Lab opened in 2017.  Interested in applying? Check out our contact page for more information!

The Shah Lab uses viruses and engineering principles to perturb and control biological networks. We are interested in exploring two major questions:

  1. How do flaviviruses hijack host machinery to facilitate their own replication and cause disease?
  2. Can we control these biological networks for biomedical and biotechnology applications?

We use complementary techniques of global proteomics, genetics, high-throughput sequencing, high-throughput animal models, microscopy and synthetic biology to tackle these questions.

March 2019: Welcome to new lab members Adam Fishburn and Matthew Kenaston

February 2019: Welcome to rotation students Adam Fishburn and Leslie Herrera!

January 2019: Marine and Priya publish a review on the systems biology of arbovirus-vector interactions in Frontiers in Cellular and Infection Microbiology!

December 2018: Priya’s postdoc work on flavivirus-host protein interactions is published in Cell!